Where To Buy Heartgard
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where to buy heartgard
SAFETYReported studies with ivermectin indicate that certain dogs of the Collie breed are more sensitive to the effects of ivermectin administered at elevated dose levels (more than 16 times the target use level) than dogs of other breeds. At elevated doses, sensitive dogs showed adverse reactions which included mydriasis, depression, ataxia, tremors, drooling, paresis, recumbency, excitability, stupor, coma and death. HeartShade Plus demonstrated no signs of toxicity at 10 times the recommended dose (60 mcg/kg) in sensitive Collies.Results of these trials and reported bioequivalence studies support the safety of HeartShade Plus products in dogs, including Collies, when used as recommended.HeartShade Plus has shown a wide margin of safety at the recommended dose level in dogs, including pregnant or breeding bitches, stud dogs and puppies aged 6 or more weeks. In clinical trials, many commonly used flea collars, dips, shampoos, anthelmintics, antibiotics, vaccines and steroid preparations have been administered with HeartShade Plus in a heartworm disease preventing program.In one trial, where some pups had parvovirus, there was a marginal reduction in efficacy against intestinal nematodes, possibly due to a change in intestinal transit time. 041b061a72